Laboratory Medicine Program


Valproic acid
(Depakene, Valproate)

Clinical Decription:
Valproic acid is a broad-spectrum anticonvulsant drug used solely or in combination with other anticonvulsant drugs for the treatment of absence seizures. It also demonstrates effectiveness in the management of generalized tonic-clonic and myoclonic seizures, as well as atypical absence, simple and complex partial and mixed grand mal and petite mal seizures.

Method: Automated method; C8000

Component Tests Used: n/a

Reference Ranges Used:
Therapeutic range: 350 - 700 umol/L : Critical Value >1000 umol/L

Specimen Type: Plasma
Collected In: Lithium heparin
Volume: 3 mL (minimum: 1 mL)

Shipping: room temperature or 4C

Special Instructions: Optimum sampling time is trough level just prior to next dose

Testing Schedule(s): on demand.

Turnaround Time: 1 day

For more information, call 416.340.5227 or 1.866.865.5227