Laboratory Medicine Program

Angiotensin II (Research only)

Clinical Decription:
Angiotensin II is the physiologically active form of angiotensin a powerful vasopressor and stimulator of aldosterone production and secretion. Angiotensin II is present in the plasma of patients with essential hypertension, but is not found in the plasma of normal subjects. This test involves extraction prior to the samples assayed by a competitive RIA method.
<br/><em>Instruction manual: Angiotensin II, American Laboratory Products Company, Ltd, 1997 Davis FA. Taber's Cyclopedic Medical Dictionary, 14 ed. Philadelphia, 1968:85 Emanuel RL, et al. Double antibody radioimmunoassay of renin activity and angiotensin II in human peripheral plasma. J Lab Clin Med, 1973; 81:632-40</em>

Method: RIA; RIA

Component Tests Used: n/a

Reference Ranges Used:
.8 - 16.0 pg/mL or 0.8 - 15.3 pmol/L

Specimen Type: Lavender EDTA
Collected In: EDTA
Volume: 5 mL (minimum: 2 mL)

Shipping: Sample on dry ice

Special Instructions: Prechill tubes on ice for 30 min. prior to collection required. Add 100 uL of Bestatin (Alpco# B-BST). Centrifuge and aliquot samples.

Testing Schedule(s): on request, but must be a minimum of 25 samples, 4 week prior arrangement.

Turnaround Time: 20 days

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For more information, call 416.340.5227 or 1.866.865.5227

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