Laboratory Medicine Program

Hereditary Breast/Ovarian/Prostate Cancer Panel

Clinical Decription:
A proportion of breast, ovarian and prostate cancer are caused by an inherited cancer predisposition. Individuals who have personal and family histories of associated cancers (which includes but is not limited to, breast cancer, ovarian cancer, prostate cancer, pancreas cancer, melanoma) may be eligible for genetic testing. Please consult the Cancer Care Ontario document outlining eligibility for genetic testing for hereditary breast/ovarian/prostate cancer (https://www.cancercareontario.ca/en/guidelines-advice/types-of-cancer/70161) and/or contact the lab for additional information. Note: This is a blood test for individuals with clinical and family histories suggestive of an inherited cancer syndrome. It is not a tumour test for somatic gene variants that provide information about diagnostics, prognostics or therapeutics.

Method: Next-Generation Sequencing (NGS)

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: peripheral blood (EDTA)
Volume: 5 mL (minimum: 2 mL)

Shipping: room temperature or 4C

Special Instructions: Genes(ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53) See requisitions for the full list of available testing and special instructions.

Testing Schedule(s): Please call

Turnaround Time: None

For more information, call 416.340.5227 or 1.866.865.5227