Laboratory Medicine Program

Hereditary Polyposis Panel

Clinical Decription:
A proportion of individuals with polyposis are affected with a hereditary cancer predisposition syndrome. Individuals who have personal and family histories of polyposis and/or related cancers may be eligible for genetic testing. Please consult the Cancer Care Ontario document outlining eligibility for genetic testing for hereditary cancer (https://www.cancercareontario.ca/en/guidelines-advice/types-of-cancer/70161) and/or contact the lab for additional information. Note: This is a blood test for individuals with clinical and family histories suggestive of an inherited cancer syndrome. It is not a tumour test for somatic gene variants that provide information about diagnostics, prognostics or therapeutics.

Method: Next-Generation Sequencing (NGS)

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: peripheral blood (EDTA)
Volume: 5 mL (minimum: 2 mL)

Shipping: room temperature or 4C

Special Instructions: Genes(APC,BMPR1A,EPCAM*, GALNT12, GERM1*, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, RNF43, RPS20, SMAD4, STK11, TP53) See requisitions for the full list of available testing and special instructions.

Testing Schedule(s): Please call

Turnaround Time: None

For more information, call 416.340.5227 or 1.866.865.5227