Laboratory Medicine Program

Lymphoid Neoplasia: B-cell Clonality (IGH, IGK)

Clinical Decription:
The immunoglobulin (Ig) genes are comprised of numerous discontinuous coding segments that somatically rearrange to produce antibody during B cell maturation. Each mature B cell or plasma cell has a unique rearrangement profile. A reactive process often demonstrates a polyclonal expansion of B-cells with different rearrangements whereas a malignant process will demonstrate a monoclonal expansion of B-cells with identical Ig gene rearrangements.

Method: PCR

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: Peripheral Blood/Bone Marrow/FFPE
Volume: n/a

Shipping: room temperature or 4C

Special Instructions: Test will be billed to referring hospital, laboratory, physician or medical group. See requisitions for the full list of available testing and special instructions.

Testing Schedule(s): Please call

Turnaround Time: None

For more information, call 416.340.5227 or 1.866.865.5227