Laboratory Medicine Program

Large B-Cell Lymphoma: FISH Panel

Clinical Decription:
Large B-Cell Lymphomas have translocations involving the MYC, BCL2 and BCL6 genes. When a MYC translocation is present with a BCL2 and/or BCL6 translocation (e.g. Double Hit or Triple Hit Lymphoma) it indicates a likely more aggressive type of lymphoma. UHN has a reflex FISH panel for Lymphoma testing. The MYC probe is run on all samples, and only those positive for MYC translocation will have BCL2 and BCL6 testing performed.

Method: Fluorescence in situ Hybridization (FISH)

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: Peripheral Blood/Bone Marrow/FFPE
Volume: n/a

Shipping: room temperature or 4C

Special Instructions: This test will be billed to a hospital, referring laboratory, referring physician or medical group. See requisitions for the full list of available testing and special instructions.

Testing Schedule(s): Please call

Turnaround Time: None

For more information, call 416.340.5227 or 1.866.865.5227