Laboratory Medicine Program

Acute Leukemia: FLT3 PCR

Clinical Decription:

<br/><em>Mutations in the FLT3 gene such as internal tandem duplications (ITD) or variants in the tyrosine kinase domain (TKD) are frequent in acute myeloid leukemia (AML). FLT3-ITD and FLT3-TKD are sensitive to AML drugs. The presence of additional co-occurring FLT3-ITD or FLT3-TKD variants can influence clinical management of AML. Multiplex PCR with primers targeting the FLT3-ITD and FLT3-TKD variants is performed to monitor AML treatment response known as minimal residual disease monitoring. </em>

Method: PCR

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: Peripheral Blood/Bone Marrow
Volume: n/a

Shipping: room temperature or 4C

Special Instructions: See requisitions for the full list of available testing and special instructions.

Testing Schedule(s): Please call

Turnaround Time: None

For more information, call 416.340.5227 or 1.866.865.5227