Laboratory Medicine Program


Paroxysmal Nocturnal Hemoglobinuria (PNH)
(CD59, FLAER, Flow Cytometry)

Clinical Decription:
Provides high sensitivity screening of red and white blood cells for the presence of PNH clones. Detection is achieved by assessing the absence or reduction in binding of FLAER, anti-CD59 and anti-CD157, which bind to GPI-linked structures on the cell membranes.

Method: Flow Cytometry; BD FACS Lyrics

Component Tests Used: n/a

Reference Ranges Used:
Reference ranges for this test are not available online. However, they are included in all test results. For more information, please call us.

Specimen Type: Peripheral Blood
Collected In: EDTA
Volume: 3mL mL (minimum: 3mL mL)

Shipping: Room temperature

Special Instructions: Samples received greater than 48 hours from the time of collection may yield suboptimal results; requests and collections for testing should be made in alignment with stability and Flow Cytometry laboratory operating hours (business hours).

Testing Schedule(s): Monday - Thursday (0900-1700), Friday (0900-1200).

Turnaround Time: 7 days

For more information, call 416.340.5227 or 1.866.865.5227