Laboratory Medicine Program

Cystatin C

Clinical Decription:
Plasma concentration of Cystatin C is almost exclusively determined by the glomerular filtration rate (GFR), making Cystatin C an excellent indicator of GFR. There is a growing body of evidence that suggests that Cystatin C can be used to detect kidney disease at earlier stages than serum creatinine which may help facilitate prevention efforts in the elderly and those with diabetes, hypertension, or cardiovascular disease. eGFR is calculated using the 2012 CKD-EPI cystatin C equation. Following current guidelines, creatinine is also measured to provide a combined (creatinine + cystatin C) eGFR based on the 2021 CKD-EPI formula.

Method: Immunoturbidimetric; Diazyme DZ-Lite c270

Component Tests Used: n/a

Reference Ranges Used:
Cystatin C: 0.62-1.16 mg/L; eGFR: >=60 mL/min/1.73m2

Specimen Type: Serum
Volume: n/a

Shipping: None

Special Instructions: Collect whole blood by venipuncture and allow clotting. Centrifuge and separate serum as soon as possible after collection.

Testing Schedule(s): Please call

Turnaround Time: 5 days

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For more information, call 416.340.5227 or 1.866.865.5227

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