Laboratory Medicine Program

Parathyroid hormone, intact, serum
(PTH)

Clinical Decription:
In healthy individuals, PTH is secreted in response to circulating calcium ion levels. Any dip below an individual?s normal level triggers a pronounced increase in PTH secretion. Calcium levels returning to normal exert a negative feedback effect, thus inhibiting PTH secretion by the parathyroid glands. Recent assays for Intact PTH have the necessary sensitivity for detecting circulating Intact PTH in normals and for discriminating between normals and those with primary hyperparathyroidism. These assays also appear to discriminate better between primary hyperparthyroidism and hypercalcemia of malignancy compared with previous assays, and do so virtually without any significant overlap between these groups. (See package insert for more information).

Method: Automated/Manual

Component Tests Used: n/a

Reference Ranges Used:
2.0-9.4 pmol/L

Specimen Type: Lavender EDTA
Collected In: EDTA
Volume: 3 mL (minimum: 1 mL)

Shipping: 4C

Special Instructions: Centrifuge and aliquot immediately.

Testing Schedule(s): Weekly.

Turnaround Time: 5 days

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For more information, call 416.340.5227 or 1.866.865.5227

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