Laboratory Medicine Program

Gentamicin post

Clinical Decription:
Gentamicin is an aminoglycosidic antibiotic that exhibits high potency and a broad-spectrum bacterial action against both gram-negative and gram-positive organisms. It exhibits a narrow therapeutic index, which makes it hazardous, especially in patients with impaired renal function.

Method: Automated method; c8000

Component Tests Used: n/a

Reference Ranges Used:
4-10 mg/L (Therapeutic range)

Specimen Type: Heparinized plasma
Collected In: Lithium heparin
Volume: 3 mL (minimum: 1 mL)

Shipping: room temperature or 4C

Special Instructions: Do not take levels from the same limb in which the drug has been infused. Optimum sampling time: p.o Trough level just prior to next dose; p.o Peak level 8 h after last dose; I.V. Peak level 8 h after dose. Centrifuge and aliquot sample.

Testing Schedule(s): on demand.

Turnaround Time: 1 day

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