Laboratory Medicine Program

Phenytoin (Dilantin)
(Dilantin)

Clinical Decription:
Phenytoin is used in the treatment of epilepsy, particularly grand mal seizures, cortical focal seizures and temporal lobe epilepsy. Because of the narrow therapeutic index and wide inter-individual variability in the rate of phenytoin metabolism and clearance, the determination of blood levels of phenytoin is essential.
<br/><em>c8000</em>

Method: Magnetic particle ELISA; c8000

Component Tests Used: n/a

Reference Ranges Used:
40 - 80 umol/L (Therapeutic range)

Specimen Type: serum or heparinized plasma
Collected In: Lithium heparin
Volume: 3 mL (minimum: 1 mL)

Shipping: room temperature or 4C

Special Instructions: Oral dose: Optimum sampling time: p.o. trough level just prior to next dose. I.V. 1 h after dose for peak. Centrifuge and aliquot sample.

Testing Schedule(s): on demand.

Turnaround Time: 1 day

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For more information, call 416.340.5227 or 1.866.865.5227

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