Laboratory Medicine Program
Protein, urine
Clinical Decription:
The measurement of protein in urine is used mainly in the diagnosis and treatment of renal or cardiac diseases and in disorders of the thyroid gland
The measurement of protein in CSF is used mainly in the diagnosis and treatment of neurological diseases. Increases in SF protein may be due to:
 Impairment of the blood-brain barrier, so that plasma proteins leak into the SF
 Diffusion of plasma proteins, when they are increased, across a normal blood brain barrier (eg., multiple myeloma)
 Diffusion of plasma proteins, when they are increased, across a normal blood brain barrier (eg., multiple myeloma)
Synthesis of increased quantities of immunoglobulins by plasma cells within the blood-brain barrier.
<br/><em>Bayer Advia 1650 Protein package insert
Bayer Advia 1650 Manufacturer's Manual</em>
Method: Automated method; Advia
Component Tests Used: n/a
Reference Ranges Used:
Timed urine < 0.15 g/d
Specimen Type: Random or 24 hour urine
Volume: 20 mL (minimum: 10 mL)
Shipping: 4C
Special Instructions: For 24 h urine, Discard first morning sample, collect all other urine for a 24 hour period, to include second morning sample. Record volume and aliquot.
Testing Schedule(s): Please call
Turnaround Time: 1 day
For more information, call 416.340.5227 or 1.866.865.5227