Laboratory Medicine Program

Salicylate
(ASA, Acetylsalicylic acid, Aspirin)

Clinical Decription:
Salicylates are a group of compounds used as analgesics, antipyretics and anti-inflammatory agents. Most salicylate therapy is the result of self-medication. Because of its wide availability, salicylates are frequently seen in overdose cases. Proper management of salicylate poisoning, which can prevent fatalities, requires monitoring of the patient?s serum levels.
<br/><em>Dade Dimension Salicylate package insert</em>

Method: Colorimetric; C16000

Component Tests Used: n/a

Reference Ranges Used:
1.10 - 2.20 mmol/L (Therapeutic range)

Specimen Type: Plasma
Collected In: Lithium heparin
Volume: 3 mL (minimum: 1 mL)

Shipping: room temperature or 4C

Special Instructions: Therapy: Optimum sampling times: trough prior to next dose / peak 1-3 h post dose. Sustained release: Measuring trough conc. optional. Suspected overdose: estimate time of overdose before now; obtain 2nd sample 2 h after 1st to estimate absorp /peak /elim. Centrifuge and aliquot of sample.

Testing Schedule(s): on demand.

Turnaround Time: 1 day

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