Laboratory Medicine Program

Hepatitis B e Antigen
(HBeAg, HB4)

Clinical Decription:
Hepatitis B e antigen (HBeAg) is a marker of infectivity and active hepatitis B viral replication, used to assess disease progression. HBeAg typically appears around the same time or just after HBsAg in an acute infection and will be positive in chronic infection. Absence of HBeAg does not exclude active viral replication, as some patients may be anti-HBe positive with detectable HBV DNA.

Method: Chemiluminescent Microparticle Immunoassay; Abbott Alinity-i

Component Tests Used: Hepatitis B e Antigen

Reference Ranges Used:
Negative

Specimen Type: Serum
Volume: 3 mL (minimum: 1 mL)

Shipping: 2–8°C (specimens<7D) ; Frozen (specimens>7D)

Special Instructions: Ship serum at 2-8°C or frozen at -20°C or colder. Specimen is stable at 2-8°C for 7 days. May be stored on or off the clot, red blood cells, or separator gel. If sample cannot be tested within the time period above, remove serum and freeze at – 20 °C or colder.

Testing Schedule(s): Monday to Friday.

Turnaround Time: 1 business day

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For more information, call 416.340.5227 or 1.866.865.5227

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