Laboratory Medicine Program

Apolipoprotein B
(Apo B)

Clinical Decription:
Apo B is the main cholesterol carrying protein in the blood and is the ligand concerned with the uptake of cholesterol into cells by the LDL – receptor pathway. Apo B shows atherogenic signs and is thus useful for the evaluation of coronary risk. Studies have shown that there is an inverse relationship between Apo A-1 and coronary artery disease and a direct relationship with Apo B such that patients with CAD have generally reduced levels of Apo A-1 and increased levels of Apo B. The Canadian Cardiovascular Society guidelines have indicated Apo B as useful in screening and monitoring treatment.

Method: Turbidimetric; Diazyme DZ-Lite c270

Component Tests Used: n/a

Reference Ranges Used:
<= 1.20 g/L

Specimen Type: Serum
Volume: 3 mL (minimum: 1 mL)

Shipping: serum or plasma sent frozen at -10C or colder

Special Instructions: Separate from red cells within 2 hours of collection. Store and send frozen.

Testing Schedule(s): every 10 days.

Turnaround Time: 10 Business days

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For more information, call 416.340.5227 or 1.866.865.5227

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